In an era where artificial intelligence is reshaping industries from finance to entertainment, The Coca-Cola Company is harnessing its power to tackle one of the most pressing crises in the global food supply chain: the impending extinction of oranges. Best known for its fizzy flagship soda that has quenched thirsts for over a century, Coca-Cola is quietly battling a silent killer threatening its juice empire. The beverage behemoth announced this week that it has joined the Massachusetts Institute of Technology’s (MIT) Generative AI Impact Consortium as a founding member, launching an ambitious initiative dubbed “Save the Orange” to combat citrus greening disease, or Huanglongbing (HLB). This unexpected foray into AI-driven agricultural innovation underscores not just Coca-Cola’s diversification beyond carbonated drinks but also its strategic imperative to secure a vital ingredient amid a 20-year decline in U.S. orange production.
The move comes at a critical juncture for the $45 billion company, whose portfolio includes powerhouse juice brands like Minute Maid and Simply—household names synonymous with breakfast tables and school lunches. For decades, these labels have dominated the orange juice market, but their core ingredient is under siege. HLB, a bacterial scourge spread by the Asian citrus psyllid insect, has ravaged citrus groves worldwide since its U.S. debut in Florida two decades ago. Infected trees produce bitter, misshapen fruit, stunt in growth, and eventually die, leaving farmers with no cure and billions in losses. Without intervention, experts predict the global orange supply could vanish within 25 years, spelling disaster for juice processors, consumers, and the broader economy.
Coca-Cola’s entry into the MIT consortium marks a pivotal shift, blending its supply chain expertise with cutting-edge AI to accelerate solutions. The consortium, which includes tech titans like OpenAI, semiconductor leader Analog Devices (ADI), India’s Tata Group, South Korea’s SK Telecom, and TWG Global, aims to deploy generative AI for real-world challenges. Coca-Cola’s “Save the Orange” project, developed in partnership with Brazil’s Fundecitrus research lab and biotech firm Invaio Sciences, will leverage AI to simulate data, compress research timelines from years to months, and integrate agritech, biotech, and life sciences. “Citrus greening has impacted farmers for over 15 years; now it’s high time to combine Generative AI with AgriTech, Biotech, and Life Science to accelerate research and innovation,” said Pratik Thakar, Coca-Cola’s Global Vice President and Head of Generative AI, in the announcement.
This isn’t mere philanthropy; it’s a business lifeline. Orange juice remains a cornerstone of Coca-Cola’s non-carbonated portfolio, contributing significantly to its $12.5 billion in second-quarter 2025 net revenues, which rose 1% year-over-year despite a 2% dip in unit case volume. While the company doesn’t break out Minute Maid or Simply sales separately, it highlighted gains in market share for nonalcoholic ready-to-drink beverages, with juice playing a starring role. Globally, the juice, value-added dairy, and plant-based segment saw a 4% volume decline in Q2, offset by growth in Latin America but dragged by Asia Pacific. Yet, through revenue growth management strategies—like introducing affordable single-serve juice options in emerging markets—Coca-Cola added over 130 million transactions year-to-date, demonstrating resilience amid supply pressures.
The HLB crisis has been brewing for years, but its toll on U.S. production is stark. Florida, once the world’s orange powerhouse, has seen output plummet 90% from 2005 to 2023, according to the Farm Bureau, with nearly every tree infected. Nationally, the U.S. now ranks sixth in global orange production, supplying just 5% of the world’s oranges, per USDA data. From 2015 to 2024, domestic output fell at a compound annual rate of 9%, with year-over-year drops averaging 10%. The 2024-2025 season was particularly brutal: Hurricanes Debby, Helene, and Milton battered groves, leading to a 30% harvest shortfall compared to the prior year. Overall, citrus acreage in Florida shrank 55.6% from 2004 to 2023, from 748,555 acres to 332,256 acres, as growers ripped out infected trees. In the past decade alone, HLB has slashed fresh citrus markets by 21% and juice oranges by 72%.
The economic ripple effects are profound. Florida’s citrus industry, which once generated $9 billion annually, has lost billions to HLB, forcing reliance on imports from Brazil, Mexico, and Chile. But recent U.S. tariffs on foreign goods—escalating under the current administration—threaten to inflate costs and exacerbate shortages. Major brands, including Coca-Cola’s, now blend imported juice, but this patchwork solution can’t sustain indefinitely. “The loss of fresh oranges and other citrus is a real possibility, and that would seriously impact our health,” warned Carolyn Slupsky, a biochemist and nutritionist at the University of California, Davis. Beyond nutrition—citrus provides essential vitamin C and fiber—rising juice prices could squeeze consumers already facing inflation in groceries.
Coca-Cola’s “Save the Orange” initiative targets HLB head-on. The disease, first detected in Florida in 2005, clogs the trees’ vascular systems, preventing nutrient flow and yielding lopsided, green-tinged fruit that’s bitter and seedless. No cure exists, but the project will use AI to model disease spread, optimize treatments, and discover new biological defenses. Key partners include Invaio Sciences, whose Trecise treatment—a trunk-injected antibiotic—has shown promise in halting HLB progression and slashing pesticide use by up to 90%. Launched in Florida in 2023, Trecise is expanding to Brazil and Mexico. “We’ve seen firsthand the devastation of this disease, and the proven efficacy of our Trecise treatment in stopping it,” said Amy O’Shea, CEO of Invaio Sciences and CEO Partner at Flagship Pioneering. “Treatments and application technologies will be critical components of a multi-pronged coordinated effort to restore tree health, citrus production, and farmer profitability.”
The consortium’s approach mirrors collaborative “hackathons,” uniting MIT professors in computer science, data science, and public policy with industry experts. Fundecitrus, a Brazilian nonprofit, brings decades of citrus research, emphasizing science-driven innovation. “Through the ‘Save the Orange’ partnership with The Coca-Cola Company, Fundecitrus reaffirms its long-standing commitment to science-driven solutions, transparency, and innovation,” said Executive Director Antonio Juliano Ayres. Early efforts focus on AI-simulated data to fast-track gene editing and resistant tree breeding—techniques like those from USDA researchers identifying HLB-detecting genes from potatoes.
For Coca-Cola, this aligns with broader AI integration across its operations, from R&D to supply chain optimization. “This represents a best-of-the-best combination of industry practicality and academic rigor,” Thakar noted. “It also perfectly complements our commitment to make a difference by using AI in service of humanity.” The company, which employs over 700,000 worldwide through its bottling network, sees AI as a tool for sustainability, echoing initiatives like water replenishment and packaging recycling.
Yet, challenges loom. HLB’s resilience—bacteria hide deep in roots, evading sprays—has led to resistance in psyllids, prompting calls for eco-friendly alternatives. Hurricanes compound the issue, with losses from 2024 storms estimated in the hundreds of millions. Florida’s 21 certified nurseries are propagating HLB-tolerant trees, but scaling takes time. Globally, HLB has hit Brazil and China hard, too, tightening supply.
Investors view Coca-Cola’s pivot positively. Shares of KO rose 1.2% following the announcement, buoyed by Q2 results showing 5% organic revenue growth and 4% comparable EPS increase, despite volume headwinds from weather and tough comps. Analysts praise the proactive stance: “As a leading provider of fruit juice worldwide, we have a unique perspective on the critical issue of citrus greening,” said Christina Ruggiero, Coca-Cola’s President of Global Nutrition. The company stands with farmers, collaborating on viable solutions.
Ultimately, “Save the Orange” could redefine corporate responsibility in agribusiness. By merging AI with agriculture, Coca-Cola isn’t just protecting its bottom line—it’s safeguarding a staple of American diets and economies. As Thakar put it, this “demands a unique level of partnership” to avert catastrophe. Whether it succeeds, the initiative signals a future where tech giants and beverage icons unite against existential threats, one orange at a time.